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DLX1 rabbit Polyclonal Antibody

DLX1抗體
DLX1抗體應(yīng)用:WB 1:500-2000 ELISA 1:5000-20000distal-less homeobox 1(DLX1) Homo sapiens This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein is localized to the nucleus where it may function as a transcriptional regulator of signals from multiple TGF-{beta} superfamily members. The encoded protein may play a role in the control of craniofacial patterning and the differentiation and survival of inhibitory neurons in the forebrain. This gene is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 2. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],

DMA rabbit Polyclonal Antibody

DMA抗體
DMA抗體應(yīng)用:WB 1:500-2000 ELISA 1:5000-20000major histocompatibility complex, class II, DM alpha(HLA-DMA) Homo sapiens HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. [provided by RefSeq, Jul 2008],

DMBT1 rabbit Polyclonal Antibody

DMBT1抗體
DMBT1抗體應(yīng)用:IHC-p 1:50-300deleted in malignant brain tumors 1(DMBT1) Homo sapiens Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. This gene was originally isolated based on its deletion in a medulloblastoma cell line. This gene is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The encoded protein precursor is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor suppressor gene, but rather play a role in the interaction of tumor cells and the immune system. [provided by RefSeq, Mar 2016],

DMBX1 rabbit Polyclonal Antibody

DMBX1抗體
DMBX1抗體應(yīng)用:WB 1:500-2000 This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],

DMD rabbit Polyclonal Antibody

DMD抗體
DMD抗體應(yīng)用:IHC-p 1:50-300dystrophin(DMD) Homo sapiens The dystrophin gene is the largest gene found in nature, measuring 2.4 Mb. The gene was identified through a positional cloning approach, targeted at the isolation of the gene responsible for Duchenne (DMD) and Becker (BMD) Muscular Dystrophies. DMD is a recessive, fatal, X-linked disorder occurring at a frequency of about 1 in 3,500 new-born males. BMD is a milder allelic form. In general, DMD patients carry mutations which cause premature translation termination (nonsense or frame shift mutations), while in BMD patients dystrophin is reduced either in molecular weight (derived from in-frame deletions) or in expression level. The dystrophin gene is highly complex, containing at least eight independent, tissue-specific promoters and two polyA-addition sites. Furthermore, dystrophin RNA is differentially spliced, producing a range of different transcripts, encoding a large set of protein isoforms. Dystrophin (as enc

DMP1 rabbit Polyclonal Antibody

DMP1抗體
DMP1抗體應(yīng)用:WB 1:500-2000 ELISA 1:5000-20000dentin matrix acidic phosphoprotein 1(DMP1) Homo sapiens Dentin matrix acidic phosphoprotein is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. The protein contains a large number of acidic domains, multiple phosphorylation sites, a functional arg-gly-asp cell attachment sequence, and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation the protein becomes phosphorylated and is exported to the extracellular matrix, where it orchestrates mineralized matrix formation. Mutations in the gene are known to cause autosomal recessive hypophosphatemia, a disease that manifests as rickets and osteomalacia. The gene structure is conser

DMP34 rabbit Polyclonal Antibody

DMP34抗體
DMP34抗體應(yīng)用:IHC-p 1:50-200

DMRT2 rabbit Polyclonal Antibody

DMRT2抗體
DMRT2抗體應(yīng)用:WB 1:500-2000 The protein encoded by this gene belongs to the DMRT gene family, sharing a DM DNA-binding domain with Drosophila 'doublesex' (dsx) and C. elegans mab3, genes involved in sex determination in these organisms. Also, this gene is located in a region of the human genome (chromosome 9p24.3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex-determining gene(s) on chr 9. [provided by RefSeq, Apr 2010],

DMRTA rabbit Polyclonal Antibody

DMRTA抗體
DMRTA抗體應(yīng)用:WB 1:500-2000 ELISA 1:5000-20000function:May be involved in sexual development.,similarity:Belongs to the DMRT family.,similarity:Contains 1 DM DNA-binding domain.,tissue specificity:Expressed in liver, kidney, pancreas, prostate and weakly detected in testis and ovary.,

DMRTB rabbit Polyclonal Antibody

DMRTB抗體
DMRTB抗體應(yīng)用:WB 1:500-2000 ELISA 1:5000-20000similarity:Belongs to the DMRT family.,similarity:Contains 1 DM DNA-binding domain.,tissue specificity:Testis.,
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