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COMT rabbit Polyclonal Antibody

COMT抗體
COMT抗體應(yīng)用:Western Blot: 1/500 - 1/2000. ELISA: 1/20000. catechol-O-methyltransferase(COMT) Homo sapiens Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. [provided by RefSeq, Sep 2008],

Connexin 25 rabbit Polyclonal Antibody

Connexin 25抗體
Connexin 25抗體應(yīng)用:Western Blot: 1/500 - 1/2000. ELISA: 1/10000. gap junction protein beta 7(GJB7) Homo sapiens Connexins, such as GJB7, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM, Mar 2008],

Connexin 31.3 rabbit Polyclonal Antibody

Connexin 31.3抗體
Connexin 31.3抗體應(yīng)用:Western Blot: 1/500 - 1/2000. ELISA: 1/40000. gap junction protein gamma 3(GJC3) Homo sapiens This gene encodes a gap junction protein. The encoded protein, also known as a connexin, plays a role in formation of gap junctions, which provide direct connections between neighboring cells. Mutations in this gene have been reported to be associated with nonsyndromic hearing loss.[provided by RefSeq, Feb 2010],

Connexin 37 rabbit Polyclonal Antibody

Connexin 37抗體
Connexin 37抗體應(yīng)用:Western Blot: 1/500 - 1/2000. ELISA: 1/40000. gap junction protein alpha 4(GJA4) Homo sapiens This gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction. [provided by RefSeq, Jul 2008],

Connexin 43 rabbit Polyclonal Antibody

Connexin 43抗體
Connexin 43抗體應(yīng)用:Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000.gap junction protein alpha 1(GJA1) Homo sapiens This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations. [provided by RefSeq, May 2014],

Connexin 43 rabbit Polyclonal Antibody

Connexin 43抗體
Connexin 43抗體應(yīng)用:WB 1:500-2000 ,Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. gap junction protein alpha 1(GJA1) Homo sapiens This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations. [provided by RefSeq, May 2014],

Connexin 43 rabbit Polyclonal Antibody

Connexin 43抗體
Connexin 43抗體應(yīng)用:Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000.gap junction protein alpha 1(GJA1) Homo sapiens This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations. [provided by RefSeq, May 2014],

Connexin 45 rabbit Polyclonal Antibody

Connexin 45抗體
Connexin 45抗體應(yīng)用:Western Blot: 1/500 - 1/2000. ELISA: 1/40000. gap junction protein gamma 1(GJC1) Homo sapiens This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Alternatively spliced transcript variants encoding the same isoform have been described. [provided by RefSeq, Jul 2008],

Connexin 46 rabbit Polyclonal Antibody

Connexin 46抗體
Connexin 46抗體應(yīng)用:Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000.gap junction protein alpha 3(GJA3) Homo sapiens The protein encoded by this gene is a connexin and is a component of lens fiber gap junctions. Defects in this gene are a cause of zonular pulverulent cataract type 3 (CZP3). [provided by RefSeq, Jan 2010],

Connexin 47 rabbit Polyclonal Antibody

Connexin 47抗體
Connexin 47抗體應(yīng)用:Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. gap junction protein gamma 2(GJC2) Homo sapiens This gene encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1. [provided by RefSeq, Jul 2008],
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