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多克隆抗體

IL-1β rabbit Polyclonal Antibody

IL-1β抗體
IL-1β抗體應(yīng)用:Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. interleukin 1 beta(IL1B) Homo sapiens The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008],

IL-1β rabbit Polyclonal Antibody

IL-1β抗體
IL-1β抗體應(yīng)用:Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000.interleukin 1 beta(IL1B) Homo sapiens The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008],

IL-2 rabbit Polyclonal Antibody

IL-2抗體
IL-2抗體應(yīng)用:IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/5000. interleukin 2(IL2) Homo sapiens The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008],

IL-20 rabbit Polyclonal Antibody

IL-20抗體
IL-20抗體應(yīng)用:IHC-p 1:50-200, ELISA 1:10000-20000 interleukin 20(IL20) Homo sapiens The protein encoded by this gene is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis. [provided by RefSeq, Jul 2008],

IL-20 rabbit Polyclonal Antibody

IL-20抗體
IL-20抗體應(yīng)用:Western Blot: 1/500 - 1/2000. ELISA: 1/5000. interleukin 20(IL20) Homo sapiens The protein encoded by this gene is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis. [provided by RefSeq, Jul 2008],

IL-20Rα rabbit Polyclonal Antibody

IL-20Rα抗體
IL-20Rα抗體應(yīng)用:Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. interleukin 20 receptor subunit alpha(IL20RA) Homo sapiens This gene encodes a member of the type II cytokine receptor family. The encoded protein is a subunit of the receptor for interleukin 20, a cytokine that may be involved in epidermal function. The interleukin 20 receptor is a heterodimeric complex consisting of the encoded protein and interleukin 20 receptor beta. This gene and interleukin 20 receptor beta are highly expressed in skin, and are upregulated in psoriasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

IL-20Rβ rabbit Polyclonal Antibody

IL-20Rβ抗體
IL-20Rβ抗體應(yīng)用:Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. interleukin 20 receptor subunit beta(IL20RB) Homo sapiens IL20RB and IL20RA (MIM 605620) form a heterodimeric receptor for interleukin-20 (IL20; MIM 605619) (Blumberg et al., 2001 [PubMed 11163236]).[supplied by OMIM, Feb 2009],

IL-21 rabbit Polyclonal Antibody

IL-21抗體
IL-21抗體應(yīng)用:Western Blot: 1/500 - 1/2000. ELISA: 1/20000. interleukin 21(IL21) Homo sapiens This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],

IL-22 rabbit Polyclonal Antibody

IL-22抗體
IL-22抗體應(yīng)用:Western Blot: 1/500 - 1/2000. ELISA: 1/10000. function:Cytokine that contributes to the inflammatory response in vivo.,similarity:Belongs to the IL-10 family.,

IL-26 rabbit Polyclonal Antibody

IL-26抗體
IL-26抗體應(yīng)用:Western Blot: 1/500 - 1/2000. ELISA: 1/10000. interleukin 26(IL26) Homo sapiens This gene was identified by its overexpression specifically in herpesvirus samimiri-transformed T cells. The encoded protein is a member of the IL10 family of cytokines. It is a secreted protein and may function as a homodimer. This protein is thought to contribute to the transformed phenotype of T cells after infection by herpesvirus samimiri. [provided by RefSeq, Jul 2008],
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